![]() The movement is skeletonized with a coating of anthracite and ruthenium, and to make the time easier to read, the watch has large white hour and minute hand markers and a red arrow-shaped hand to indicate the chronograph. This 45 mm version comes with three major complications: a chronograph, a perpetual calendar and a moon phase. Hublot, known for developing its own high- tech materials, turns out more sapphire-crystal-cased watches than most, if not all, other brands today, despite how difficult they are to produce. Hublot: Big Bang Unico Perpetual Calendar Sapphire.There is only one-of 30-left in the world of the DLC-coated version of the saphire crystal watch that is secured with Super-LumiNova columns, which illuminate like space beams. Unidentified flying object or centuries-old mechanics encapsulated for the future? While Bulgari is accustomed to dreaming up out-of-this-world creations, its watchmakers outdid themselves in 2016, when they introduced this 53 mm skeletonized tourbillon timepiece with sapphire bridges. Bulgari: Tourbillon Saphir Gerald Genta Special Edition. ![]() Taking a spin in the world of haute horlogerie, the company introduced the BR-X1 Tourbillon Chronograph, but the latest version comes in an all-saphire-crystal case to highlight the skeletonized movement for extra visual effect. When Bell & Ross debuted the original version of this beauty in 2014, the watchmaker proved it was bent on spreading its wings beyond its aeronautical tool watches. Bell & Ross: BR-X1 Chronograph Tourbillon Sapphire.Even if its functions aren’t clear to you, its cosmic magnificence, set against an aventurine backdrop, needs no explanation. ![]() The piece includes an hours and minutes dial rotating every 10 minutes on the central axis, a one-carat diamond with 288 facets spinning in 30 seconds on its axis, a magnesium-lacquered globe turning in 30 seconds, a gravitational tourbillon cage revolving alternately in two directions and a patented differential gears system. Like a mini mechanical universe for your wrist, the entire inner workings of this watch move around the circumference of the case-visible from every angle. Among the mesmerizing movements worth featuring in sapphire crystal, surely Jacob & Co.’s Astronomia takes the cake. ![]()
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![]() Depending on these choices, the resulting tandem mass (MS/MS) spectra vary in fragmentation propensities and precision. Empowered by these changes, MS researchers now have diverse choices with respect to the questions: ‘what fragmentation method to use?’, ‘how accurate should be the measurements of the mass-to-charge ( m/z) ratios?’, ‘what proteases to use?’ and ‘what post-translational modification (PTM) to focus on (for example, phosphorylation)?’. Although trypsin remains a dominant protease in proteomics studies, digesting proteins with diverse proteases is becoming popular 1. New fragmentation technologies have emerged and high-precision mass spectrometers like Orbitrap have become widely available. ![]() ![]() Mass spectrometry (MS) instruments and experimental protocols have greatly advanced over the last decade. We emphasize that although MS-GF+ is not specifically designed for any particular experimental set-up, it improves on the performance of tools specifically designed for these applications (for example, specialized tools for phosphoproteomics). For all these data sets, MS-GF+ significantly increases the number of identified peptides compared with commonly used methods for peptide identifications. We benchmark MS-GF+ using diverse spectral data sets: (i) spectra of varying fragmentation methods (ii) spectra of multiple enzyme digests (iii) spectra of phosphorylated peptides and (iv) spectra of peptides with unusual fragmentation propensities produced by a novel alpha-lytic protease. We present a database search tool MS-GF+ that is sensitive (it identifies more peptides than most other database search tools) and universal (it works well for diverse types of spectra, different configurations of MS instruments and different experimental protocols). Mass spectrometry (MS) instruments and experimental protocols are rapidly advancing, but the software tools to analyse tandem mass spectra are lagging behind. ![]() ![]() At the bottom is a message log, which displays the text commands and responses between gFTP and the remote server. Below there is a transfer queue that shows the real-time status of each queued or active file transfer. The GUI uses a double-paned layout, with the local filesystem in the left pane and the remote filesystem in the right pane. There is support for the FTP, FTPS (control connection only), HTTP, HTTPS, SFTP, and FSP protocols as well as FTP and HTTP proxy server support and FXP file transfers (transferring files between two remote servers via FTP). gFTP is released under the terms of the GPL and has been translated into 45 languages. It includes both a graphical user interface (GUI), which utilizes the GTK+ graphical toolkit, and a command-line interface. It is most used on Unix-like systems such as Linux, macOS, and Sony PlayStation 3. GFTP is a free and open-source multithreaded File Transfer Protocol client program. Amharic, Arabic, Assamese, Azerbaijani, Belarusian, Bulgarian, Bengali, Bengali (India), Bosnian, Catalan, Catalan (Valencia), Czech, Danish, German, Dzongkha, Greek, English (Canada), English (Great Britain), Esperanto, Spanish, Estonian, Basque, Finnish, French, Irish, Galician, Gujarati, Hebrew, Hindi, Croatian, Hungarian, Italian, Japanese, Kannada, Korean, Lithuanian, Latvian, Macedonian, Malayalam, Marathi, Malay, Norwegian Bokmål, Nepali, Dutch, Occitan, Oriya, Punjabi, Polish, Portuguese, Portuguese (Brazil), Romanian, Russian, Kinyarwanda, Slovak, Slovenian, Albanian, Serbian, Serbian (Latin), Swedish, Tamil, Telugu, Thai, Turkish, Ukrainian, Chinese (Simplified, PRC), Chinese (Traditional, Hong Kong S.A.R.), Chinese (Traditional, Taiwan) ![]() ![]() Now each variable has its own column, and there is a row for every document in the project. ![]() In Figure 12.1.3, above, we have toggled to the Data Editor view of the same window. This button has the label “Variable view Ctrl+ O” in both displays but is only highlighted in the list of variables version. In the data editor version you can add values for each variable to the cases or respondents. In the list of variables version you can create new variables and adjust the parameters that define them. This toggles between two displays, the list of variables and the data editor. Now look at the toolbar in this window and in particular the 5 th icon from the left. Each variable has its own row in this window and the columns are used to define various parameters for them.įigure 12.1.2 – List of Document Variables window Any variables created by the user (and that includes those imported as part of the survey data) have a blue box. Note in Figure 12.1.2 that some variables have been created by the program, these have a red box in the first column of the table. Here some user-defined variables have been added already (if you have imported the survey data element of this case study into your project you should also have something similar to these variables). This opens a window that is illustrated in Figure 12.1.2 below. Use the menu option “Variables > List of document variables” to open the routine. ![]() ![]() This exercise will work through the manual procedure so that you can become familiar with how these variables work before practising a more ambitious import routine in the next exercise.įigure 12.1.1 – Variables menu Using the document variables windows You can create new variables and add values for each case manually within MAXQDA11, or you can import several variables and the values for multiple cases in a special routine if you have this data arranged in a spreadsheet file. You can then use these variables in subsequent interrogations of your data to separate and compare the data for subgroups of your sample that share values for selected characteristics.Ĭode variables will be discussed in a separate exercise (Ch12 Ex3), they are useful when you have multiple cases in a document (such as a focus group transcript) and you have used structural codes to identify the contributions made by different speakers for whom you also want to record factual characteristics. You should use document variables where a case is represented in your project data by a whole document, such as an interview transcript, so that you can record facts about each respondent such as their gender or age through an appropriate variable. There are two types of variable available, document variables and code variables. These are accessed from the top bar of menu options or through 4 icons on the standard toolbar (the toolbar icons are displayed in the menu, as can be seen in Figure 12.1.1 below). In MAXQDA11 the term used for the factual characteristics of cases or respondents is “Variables”. ![]() |